Cell Disruption, it's in our Genes

Trade-in your French Press for a new cell disruptor 

One Shot

  • Ultra low loss
  • Quick and easy to use
  • IQ/OQ available on request
  • Contained during operation
  • Pressure consistent and stable during disruption cycle
  • Easily dismantled for manual cleaning and autoclaving
  • Allows loading of solid sample, cell paste or suspended sample
  • Disrupter head mounted in stainless steel tray to avoid spillage 
  • Disruption pressure range of 1KPSI through to 40KPSI as standard

Process 1-20ml per shot depending on pressure

40 KPSI (2700 bar)       30 KPSI (2000 bar)       20 KPSI (1350 bar)       15 KPSI (1000 bar)

             1-8ml                                1.5-10.5ml                               2-16ml                            3-20.5ml

Multi Shot

  • Ultra low loss
  • Quick and easy to use
  • IQ/OQ available on request
  • Contained during operation
  • Pressure consistent and stable during disruption cycle
  • Easily dismantled for manual cleaning and autoclaving
  • Allows loading of solid sample, cell paste or suspended sample
  • Disrupter head mounted in stainless steel tray to avoid spillage 
  • Disruption pressure range of 1KPSI through to 40KPSI as standard

Ideal for samples between 1-80ml

5 cycles = 1 process  (1-40ml per process)

TS-Series Benchtop

  • Incorporates our unique disruption head, precise hydraulic operating control system with an automatically supplied, continuous flow Cell Disrupter.
  • Disruption pressure easily and accurately set and displayed digitally with a range of 1KPSI through to 40KPSI as standard.
  • Touch screen control of disruption cycle, automatic shut down when process complete.
  • Cell Disrupter controls peristaltic process pump for automatic supply of sample. Process pump available on request.
  • Disruption head mounted in stainless steel tray to avoid spillage.
  • Partial containment and simple externally controlled CIP.
  • Internal relief valve fitted for reverse flow of cleaning fluids.
  • Various flow rates are available depending on desired maximum pressure and power rating, alternative pressure heads available on request.
  • Pressure consistent and stable during disruption cycle.
  • Full bio-containment inlet and outlet options available upon request.
  • IQ/OQ available on request.

Flow Rates vs Maximum Pressure

Power

 40 KPSI (2700 bar)      30 KPSI (2000 bar)       20 KPSI (1350 bar)       15 KPSI (1000 bar)

0.75 kw

             40ml/min                         55ml/min                              80ml/min                        115ml/min  

1.1  kw

          100ml/min                      120ml/min                            180ml/min                       255ml/min  

Temperature Control: Disruption head is surrounded by a unique cooling jacket. Bath circulator or chiller is recommended.

TS-Series Cabinet

  • Incorporates our unique disruption head, precise hydraulic operating control system with an automatically supplied, continuous flowing Cell Disrupter.
  • Disruption pressure easily and accurately set and displayed digitally with a range of 1KPSI through to 40KPSI as standard.
  • Touch screen control of disruption cycle, automatic shut down when process complete.
  • Cell Disrupter controls peristaltic process pump for automatic supply of sample. Process pump available on request.
  • Disruption head mounted in stainless steel tray to avoid spillage.
  • Partial containment and simple externally controlled CIP.
  • Internal relief valve fitted for reverse flow of cleaning fluids.
  • Various flow rates are available depending on desired maximum pressure and power rating, alternative pressure heads available on request.
  • Pressure consistent and stable during disruption cycle.
  • Full bio-containment inlet and outlet options available on request.
  • IQ/OQ available on request.

Flow Rates vs Maximum Pressure

Power

 40 KPSI (2700 bar)      30 KPSI (2000 bar)       20 KPSI (1350 bar)       15 KPSI (1000 bar)

2.2 kw

          190ml/min                      240ml/min                            300ml/min                      310ml/min  

4  kw

          405ml/min                      430ml/min                            440ml/min                       565ml/min  

Temperature Control: Disruption head is surrounded by a unique cooling jacket. Bath circulator or chiller is recommended.

HAIVA
(High Area Inlet Valve Arrangement)

  • Incorporates our unique disruption head, precise hydraulic operating and control system with an automatically supplied, continuous flowing Cell disrupter.
  • Designed to process viscous or awkward samples such as filamentous fungi.
  • Dimensions and specifications same as the standard continuous flow models.
  • Available as an alternative inlet arrangement on all continuous flow models.
  • Inlet area 5 times larger than standard machine.
  • Automatically guards against build up on inlet passage way

Flow Rates vs Maximum Pressure

Power

 40 KPSI (2700 bar)      30 KPSI (2000 bar)       20 KPSI (1350 bar)       15 KPSI (1000 bar)

0.75 kw

             40ml/min                         55ml/min                              80ml/min                        105ml/min  

1.1  kw

          100ml/min                      140ml/min                            200ml/min                       275ml/min  

2.2 kw

          170ml/min                      235ml/min                            340ml/min                      470ml/min  

4  kw

          300ml/min                      415ml/min                            600ml/min                       825ml/min  

B&C-Series 

  • Incorporates our unique disruption head and precise hydraulic operating and control system with CIP and SIP capability
  • Disruption pressure easily and accurately set and displayed digitally with a range of 1KPSI through to 40KPSI as standard
  • Cell Disrupter controls peristaltic process pump for automatic supply of larger samples. Process pump available on request
  • Fully contained and having internal ports and drain ports to allow CIP and SIP
  • The “B Series” alllows the CIP and SIP to be manually operated
  • The “C Series” includes all valves which can be tailored to customers requirements and validated
  • IQ/OQ available on request
  • Various flow rates are available depending on maximum pressure and power rating, alternative pressure heads available on request
  • Pressure consistent and stable during disruption cycle
  • Temperature control and dimensions as per TS Series
  • Validation: Industry standard validations available on request

Flow Rates vs Maximum Pressure

Power

 40 KPSI (2700 bar)      30 KPSI (2000 bar)       20 KPSI (1350 bar)       15 KPSI (1000 bar)

1.1 kw

          100ml/min                      120ml/min                            180ml/min                      225ml/min  

2.2 kw

          190ml/min                      240ml/min                            300ml/min                      310ml/min  

4  kw

          405ml/min                      430ml/min                            440ml/min                      565ml/min  

Temperature Control: Disruption head is surrounded by a unique cooling jacket. Bath circulator or chiller is recommended.

HFR system

The HFR Range are the ideal production models, with flow rates of up to 150L/hour.

  • Incorporates our unique disruption mechanism and precise hydraulic operating control system
  • Disruption pressure easily and accurately set and displayed digitally with a range of up to 40Kpsi as standard
  • Flow rate up to 150 L/hr at maximum pressure
  • Automatic shut down when process is complete
  • Various flow rates are available depending on desired maximum pressure
  • Pressure consistent and stable during the disruption cycle
  • Various fittings available for inlet and outlet, allowing direct connections to up- stream and downstream equipment
  • Performance comparable to existing range of Constant Systems Ltd cell disruptors
  • Materials in contact with sample—316L and F51 duplex stainless steel or equiv- alent, EPDM *
  • IQ/OQ available on request
       

ADU

The ADU is the ideal research and production model, with flow rates of up to 20L/hr dependant on pressure and flow of compressed air supply.

  • Up to 90% lysis efficiency with Saccharomyces cerevisiae
  • Lysis efficiency comparable with existing TS models with equivalent parameter configuration
  • This portable system is a self contained air-driven unit
  • Configuration optimisable to maximise lysis efficiency of different cell types.
  • Various flow rates are available depending on pressure and flow of compressed air
  • Materials—Stainless steel wetted parts, Teflon, Viton and U-PE *
  • IQ/OQ available on request